A rare case of sporadic mismatch repair deficient pancreatic ductal adenocarcinoma that responded to ipilimumab and nivolumab combination treatment: case report

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignant disease with a poor prognosis. Despite high efficacy in multiple cancers, immunotherapy has had very little success in treating PDAC due to unfavorable characteristics such as low tumor mutational burden (TMB), low micros...

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Detalles Bibliográficos
Autores principales: Han, Margaret Y., Borazanci, Erkut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10007950/
https://www.ncbi.nlm.nih.gov/pubmed/36915432
http://dx.doi.org/10.21037/jgo-22-587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10007950/
https://www.ncbi.nlm.nih.gov/pubmed/36915432
http://dx.doi.org/10.21037/jgo-22-587

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