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Comprehensive Genomic Profiling Identifies FAT1 as a Negative Regulator of EMT, CTCs, and Metastasis of Hepatocellular Carcinoma

BACKGROUND: FAT atypical cadherin 1 (FAT1) acts as a tumor suppressor or oncogene, which regulates cell adherence, proliferation, motility, and actin kinetics. FAT1 gene expression is closely related to hepatocarcinogenesis; however, the function and mechanism of FAT1 in hepatocellular carcinoma (HC...

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Detalles Bibliográficos
Autores principales: Huang, Zi-Li, Zhang, Ping-Bao, Zhang, Jun-Tao, Li, Feng, Li, Ting-Ting, Huang, Xiu-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10007982/
https://www.ncbi.nlm.nih.gov/pubmed/36915393
http://dx.doi.org/10.2147/JHC.S398573