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A systematic evaluation of normalization methods and probe replicability using infinium EPIC methylation data

BACKGROUND: The Infinium EPIC array measures the methylation status of > 850,000 CpG sites. The EPIC BeadChip uses a two-array design: Infinium Type I and Type II probes. These probe types exhibit different technical characteristics which may confound analyses. Numerous normalization and pre-proc...

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Detalles Bibliográficos
Autores principales: Welsh, H., Batalha, C. M. P. F., Li, W., Mpye, K. L., Souza-Pinto, N. C., Naslavsky, M. S., Parra, E. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008016/
https://www.ncbi.nlm.nih.gov/pubmed/36906598
http://dx.doi.org/10.1186/s13148-023-01459-z