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A systematic evaluation of normalization methods and probe replicability using infinium EPIC methylation data
BACKGROUND: The Infinium EPIC array measures the methylation status of > 850,000 CpG sites. The EPIC BeadChip uses a two-array design: Infinium Type I and Type II probes. These probe types exhibit different technical characteristics which may confound analyses. Numerous normalization and pre-proc...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008016/ https://www.ncbi.nlm.nih.gov/pubmed/36906598 http://dx.doi.org/10.1186/s13148-023-01459-z |