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Protocol and statistical analysis plan for the Antibiotic Choice On ReNal outcomes (ACORN) randomised clinical trial

INTRODUCTION: Antibiotics are time-critical in the management of sepsis. When infectious organisms are unknown, patients are treated with empiric antibiotics to include coverage for gram-negative organisms, such as antipseudomonal cephalosporins and penicillins. However, in observational studies, so...

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Detalles Bibliográficos
Autores principales: Qian, Edward Tang, Casey, Jonathan D, Wright, Adam, Wang, Li, Siemann, Justin, Dear, Mary Lynn, Stollings, Joanna, Lloyd, Bradley Daniel, Seitz, Kevin, Nelson, George, Wright, Patty, Siew, Edward D, Dennis, Bradley, Wrenn, Jesse, Andereck, Jonathan, Self, Wesley H, Semler, Matthew W, Rice, Todd W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008324/
https://www.ncbi.nlm.nih.gov/pubmed/36898748
http://dx.doi.org/10.1136/bmjopen-2022-066995