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Protocol and statistical analysis plan for the Antibiotic Choice On ReNal outcomes (ACORN) randomised clinical trial

INTRODUCTION: Antibiotics are time-critical in the management of sepsis. When infectious organisms are unknown, patients are treated with empiric antibiotics to include coverage for gram-negative organisms, such as antipseudomonal cephalosporins and penicillins. However, in observational studies, so...

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Detalhes bibliográficos
Principais autores: Qian, Edward Tang, Casey, Jonathan D, Wright, Adam, Wang, Li, Siemann, Justin, Dear, Mary Lynn, Stollings, Joanna, Lloyd, Bradley Daniel, Seitz, Kevin, Nelson, George, Wright, Patty, Siew, Edward D, Dennis, Bradley, Wrenn, Jesse, Andereck, Jonathan, Self, Wesley H, Semler, Matthew W, Rice, Todd W
Formato: Online Atigo Texto
Idioma:English
Publicado em: BMJ Publishing Group 2023
Assuntos:
Acesso em linha:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008324/
https://www.ncbi.nlm.nih.gov/pubmed/36898748
http://dx.doi.org/10.1136/bmjopen-2022-066995