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Interaction between tumor cell TNFR2 and monocyte membrane-bound TNF-α triggers tumorigenic inflammation in neuroblastoma

BACKGROUND: Tumor progression and resistance to therapy in children with neuroblastoma (NB), a common childhood cancer, are often associated with infiltration of monocytes and macrophages that produce inflammatory cytokines. However, the mechanism by which tumor-supportive inflammation is initiated...

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Detalles Bibliográficos
Autores principales: Tomolonis, Julie A, Xu, Xin, Dholakia, Kshiti H, Zhang, Chunchao, Guo, Linjie, Courtney, Amy N, Wang, Siyue, Balzeau, Julien, Barragán, Gabriel A, Tian, Gengwen, Di Pierro, Erica J, Metelitsa, Leonid S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008329/
https://www.ncbi.nlm.nih.gov/pubmed/36882225
http://dx.doi.org/10.1136/jitc-2022-005478