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Aging and memory are altered by genetically manipulating lactate dehydrogenase in the neurons or glia of flies
The astrocyte-neuron lactate shuttle hypothesis posits that glial-generated lactate is transported to neurons to fuel metabolic processes required for long-term memory. Although studies in vertebrates have revealed that lactate shuttling is important for cognitive function, it is uncertain if this f...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008500/ https://www.ncbi.nlm.nih.gov/pubmed/36849157 http://dx.doi.org/10.18632/aging.204565 |