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RIOK3 promotes mTORC1 activation by facilitating SLC7A2-mediated arginine uptake in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy with a poor prognosis. Reprogramming of amino acid metabolism is one of the characteristics of PDAC, in which arginine metabolism is significantly altered in PDAC cells and is involved in important signaling pathways. Current...

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Detalles Bibliográficos
Autores principales: Qin, Henan, Sun, Rui, Guo, Xin, Fang, Lei, Xu, Mengyuan, Teng, Yibin, Zhen, Ning, Wang, Aman, Liu, Jiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008507/
https://www.ncbi.nlm.nih.gov/pubmed/36880835
http://dx.doi.org/10.18632/aging.204528