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Inflammatory CSF profiles and longitudinal development of cognitive decline in sporadic and GBA-associated PD

Inflammation modifies the incidence and progression of Parkinson’s disease (PD). By using 30 inflammatory markers in CSF in 498 people with PD and 67 people with dementia with Lewy bodies (DLB) we show that: (1) levels of ICAM-1, Interleukin-8, MCP-1, MIP-1 beta, SCF and VEGF were associated with cl...

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Detalles Bibliográficos
Autores principales: Lerche, Stefanie, Zimmermann, Milan, Roeben, Benjamin, Wurster, Isabel, Fries, Franca Laura, Deuschle, Christian, Waniek, Katharina, Lachmann, Ingolf, Jakobi, Meike, Joos, Thomas O., Knorpp, Thomas, Schneiderhan-Marra, Nicole, Brockmann, Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008539/
https://www.ncbi.nlm.nih.gov/pubmed/36906614
http://dx.doi.org/10.1038/s41531-023-00476-2