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DNA-dependent protein kinase catalytic subunit (DNA-PKcs) drives chronic kidney disease progression in male mice

Kidney injury initiates epithelial dedifferentiation and myofibroblast activation during the progression of chronic kidney disease. Herein, we find that the expression of DNA-PKcs is significantly increased in the kidney tissues of both chronic kidney disease patients and male mice induced by unilat...

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Detalles Bibliográficos
Autores principales: Yang, Yunwen, Liu, Suwen, Wang, Peipei, Ouyang, Jing, Zhou, Ning, Zhang, Yue, Huang, Songming, Jia, Zhanjun, Zhang, Aihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008567/
https://www.ncbi.nlm.nih.gov/pubmed/36906617
http://dx.doi.org/10.1038/s41467-023-37043-5