STOML2 restricts mitophagy and increases chemosensitivity in pancreatic cancer through stabilizing PARL-induced PINK1 degradation

Pancreatic cancer remains one of the most lethal diseases with a relatively low 5-year survival rate, and gemcitabine-based chemoresistance occurs constantly. Mitochondria, as the power factory in cancer cells, are involved in the process of chemoresistance. The dynamic balance of mitochondria is un...

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Detalles Bibliográficos
Autores principales: Qin, Cheng, Wang, Yuanyang, Zhao, Bangbo, Li, Zeru, Li, Tianyu, Yang, Xiaoying, Zhao, Yutong, Wang, Weibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008575/
https://www.ncbi.nlm.nih.gov/pubmed/36906621
http://dx.doi.org/10.1038/s41419-023-05711-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008575/
https://www.ncbi.nlm.nih.gov/pubmed/36906621
http://dx.doi.org/10.1038/s41419-023-05711-5

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