Different MAPT haplotypes influence expression of total MAPT in postmortem brain tissue

The MAPT gene, encoding the microtubule-associated protein tau on chromosome 17q21.31, is result of an inversion polymorphism, leading to two allelic variants (H1 and H2). Homozygosity for the more common haplotype H1 is associated with an increased risk for several tauopathies, but also for the syn...

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Detalles Bibliográficos
Autores principales: Tauber, Christina V., Schwarz, Sigrid C., Rösler, Thomas W., Arzberger, Thomas, Gentleman, Steve, Windl, Otto, Krumbiegel, Mandy, Reis, André, Ruf, Viktoria C., Herms, Jochen, Höglinger, Günter U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008602/
https://www.ncbi.nlm.nih.gov/pubmed/36906636
http://dx.doi.org/10.1186/s40478-023-01534-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008602/
https://www.ncbi.nlm.nih.gov/pubmed/36906636
http://dx.doi.org/10.1186/s40478-023-01534-9

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