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Rare sugar l-sorbose exerts antitumor activity by impairing glucose metabolism

Rare sugars are monosaccharides with low natural abundance. They are structural isomers of dietary sugars, but hardly be metabolized. Here, we report that rare sugar l-sorbose induces apoptosis in various cancer cells. As a C-3 epimer of d-fructose, l-sorbose is internalized via the transporter GLUT...

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Detalles Bibliográficos
Autores principales: Xu, Hui-Lin, Zhou, Xiaoman, Chen, Shuai, Xu, Si, Li, Zijie, Nakanishi, Hideki, Gao, Xiao-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008635/
https://www.ncbi.nlm.nih.gov/pubmed/36906698
http://dx.doi.org/10.1038/s42003-023-04638-z