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Tumor cell plasticity in targeted therapy-induced resistance: mechanisms and new strategies

Despite the success of targeted therapies in cancer treatment, therapy-induced resistance remains a major obstacle to a complete cure. Tumor cells evade treatments and relapse via phenotypic switching driven by intrinsic or induced cell plasticity. Several reversible mechanisms have been proposed to...

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Detalles Bibliográficos
Autores principales: Shi, Zhen-Duo, Pang, Kun, Wu, Zhuo-Xun, Dong, Yang, Hao, Lin, Qin, Jia-Xin, Wang, Wei, Chen, Zhe-Sheng, Han, Cong-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008648/
https://www.ncbi.nlm.nih.gov/pubmed/36906600
http://dx.doi.org/10.1038/s41392-023-01383-x