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Apolipoprotein L3 enhances CD8+ T cell antitumor immunity of colorectal cancer by promoting LDHA-mediated ferroptosis

Aim: Colorectal cancer (CRC) is the leading cause of cancer associated death worldwide and immune checkpoint blockade therapy only benefit a small set of CRC patients. Tumor ferroptosis of CRC reflected immune-activation in our previous findings. Understanding the mechanisms underlying how to bolste...

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Detalles Bibliográficos
Autores principales: Lv, Yang, Tang, WenTao, Xu, YuQiu, Chang, WenJu, Zhang, ZhiYuan, Lin, Qi, Ji, MeiLing, Feng, QingYang, He, GuoDong, Xu, JianMin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008698/
https://www.ncbi.nlm.nih.gov/pubmed/36923931
http://dx.doi.org/10.7150/ijbs.74985