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Role of p53 in breast cancer progression: An insight into p53 targeted therapy

The transcription factor p53 is an important regulator of a multitude of cellular processes. In the presence of genotoxic stress, p53 is activated to facilitate DNA repair, cell cycle arrest, and apoptosis. In breast cancer, the tumor suppressive activities of p53 are frequently inactivated by eithe...

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Detalles Bibliográficos
Autores principales: Marvalim, Charlie, Datta, Arpita, Lee, Soo Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008729/
https://www.ncbi.nlm.nih.gov/pubmed/36923534
http://dx.doi.org/10.7150/thno.81847