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FGF19-mediated ELF4 overexpression promotes colorectal cancer metastasis through transactivating FGFR4 and SRC

Background: Metastasis accounts for the high lethality of colorectal cancer (CRC) patients. Unfortunately, the molecular mechanism manipulating metastasis in CRC is still elusive. Here, we investigated the function of E74-like factor 4 (ELF4), an ETS family member, in facilitating CRC progression. M...

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Bibliografische gegevens
Hoofdauteurs: Chen, Xilang, Chen, Jie, Feng, Weibo, Huang, Wenjie, Wang, Guodong, Sun, Mengyu, Luo, Xiangyuan, Wang, Yijun, Nie, Yongzhan, Fan, Daiming, Wu, Kaichun, Xia, Limin
Formaat: Online Artikel Texto
Taal:English
Gepubliceerd in: Ivyspring International Publisher 2023
Onderwerpen:
Online toegang:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008733/
https://www.ncbi.nlm.nih.gov/pubmed/36923538
http://dx.doi.org/10.7150/thno.82269