Repurposing 1,2,4-oxadiazoles as SARS-CoV-2 PLpro inhibitors and investigation of their possible viral entry blockade potential

Although vaccines are obviously mitigating the COVID-19 pandemic diffusion, efficient complementary antiviral agents are urgently needed to combat SARS-CoV-2. The viral papain-like protease (PLpro) is a promising therapeutic target being one of only two essential proteases crucial for viral replicat...

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Detalles Bibliográficos
Autores principales: Ayoup, Mohammed Salah, ElShafey, Mariam M., Abdel-Hamid, Hamida, Ghareeb, Doaa A., Abu-Serie, Marwa M., Heikal, Lamia A., Teleb, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008816/
https://www.ncbi.nlm.nih.gov/pubmed/36966652
http://dx.doi.org/10.1016/j.ejmech.2023.115272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008816/
https://www.ncbi.nlm.nih.gov/pubmed/36966652
http://dx.doi.org/10.1016/j.ejmech.2023.115272

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