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Amplifying the efficacy of ALA-based prodrugs for photodynamic therapy using nanotechnology

5-aminolevulinic acid (ALA) is a clinically approved prodrug involved in intracellular Heme biosynthesis to produce the natural photosensitizer (PS) Protoporphyrin IX (PpIX). ALA based photodynamic therapy (PDT) has been used to treat various malignant and non-malignant diseases. However, natural AL...

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Detalles Bibliográficos
Autores principales: Lou, Liang, Zhou, Shizhe, Tan, Sijia, Xiang, Menghua, Wang, Wei, Yuan, Chuang, Gao, Liqian, Xiao, Qicai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008889/
https://www.ncbi.nlm.nih.gov/pubmed/36923350
http://dx.doi.org/10.3389/fphar.2023.1137707