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Microbiota-induced regulatory T cells associate with FUT2-dependent susceptibility to rotavirus gastroenteritis

The FUT2 α1,2fucosyltransferase contributes to the synthesis of fucosylated glycans used as attachment factors by several pathogens, including noroviruses and rotaviruses, that can induce life-threatening gastroenteritis in young children. FUT2 genetic polymorphisms impairing fucosylation are strong...

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Detalles Bibliográficos
Autores principales: Godefroy, Emmanuelle, Barbé, Laure, Le Moullac-Vaidye, Béatrice, Rocher, Jézabel, Breiman, Adrien, Leuillet, Sébastien, Mariat, Denis, Chatel, Jean-Marc, Ruvoën-Clouet, Nathalie, Carton, Thomas, Jotereau, Francine, Le Pendu, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008897/
https://www.ncbi.nlm.nih.gov/pubmed/36922975
http://dx.doi.org/10.3389/fmicb.2023.1123803