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CircRNA_0075723 protects against pneumonia-induced sepsis through inhibiting macrophage pyroptosis by sponging miR-155-5p and regulating SHIP1 expression

INTRODUCTION: Circular RNAs (circRNAs) have been linked to regulate macrophage polarization and subsequent inflammation in sepsis. However, the underlying mechanism and the function of circRNAs in macrophage pyroptosis in pneumonia-induced sepsis are still unknown. METHODS: In this study, we screene...

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Detalles Bibliográficos
Autores principales: Yang, Dianyin, Zhao, Dongyang, Ji, Jinlu, Wang, Chunxue, Liu, Na, Bao, Xiaowei, Liu, Xiandong, Jiang, Sen, Zhang, Qianqian, Tang, Lunxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008927/
https://www.ncbi.nlm.nih.gov/pubmed/36923408
http://dx.doi.org/10.3389/fimmu.2023.1095457