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Lack of STAT1 co-operative DNA binding protects against adverse cardiac remodelling in acute myocardial infarction

In this study, we addressed the functional significance of co-operative DNA binding of the cytokine-driven transcription factor STAT1 (signal transducer and activator of transcription 1) in an experimental murine model of acute myocardial infarction (MI). STAT1 knock-in mice expressing a phenylalani...

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Detalles Bibliográficos
Autores principales: Doudin, Asmma, Riebeling, Theresa, Staab, Julia, Menon, Priyanka Rajeev, Lühder, Fred, Wirths, Oliver, Vinkemeier, Uwe, Ivetic, Aleksandar, Meyer, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008942/
https://www.ncbi.nlm.nih.gov/pubmed/36923955
http://dx.doi.org/10.3389/fcvm.2023.975012