Cargando…
Lack of STAT1 co-operative DNA binding protects against adverse cardiac remodelling in acute myocardial infarction
In this study, we addressed the functional significance of co-operative DNA binding of the cytokine-driven transcription factor STAT1 (signal transducer and activator of transcription 1) in an experimental murine model of acute myocardial infarction (MI). STAT1 knock-in mice expressing a phenylalani...
Autores principales: | Doudin, Asmma, Riebeling, Theresa, Staab, Julia, Menon, Priyanka Rajeev, Lühder, Fred, Wirths, Oliver, Vinkemeier, Uwe, Ivetic, Aleksandar, Meyer, Thomas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008942/ https://www.ncbi.nlm.nih.gov/pubmed/36923955 http://dx.doi.org/10.3389/fcvm.2023.975012 |
Ejemplares similares
-
An inhibitory effect on the nuclear accumulation of phospho-STAT1 by its unphosphorylated form
por: Menon, Priyanka Rajeev, et al.
Publicado: (2022) -
Evaluation of the putative lymphoma-associated point mutation D427H in the STAT3 transcription factor
por: Behrendsen, Lena Sophie, et al.
Publicado: (2022) -
DNA binding reduces the dissociation rate of STAT1 dimers and impairs the interdimeric exchange of protomers
por: Riebeling, Theresa, et al.
Publicado: (2014) -
Getting the message across, STAT! Design principles of a molecular signaling circuit
por: Vinkemeier, Uwe
Publicado: (2004) -
On the role of STAT1 and STAT6 ADP-ribosylation in the regulation of macrophage activation
por: Begitt, Andreas, et al.
Publicado: (2018)