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Exploring the mechanism of physcion-1-O-β-D-monoglucoside against acute lymphoblastic leukaemia based on network pharmacology and experimental validation

OBJECTIVE: To explore the mechanism of PG against acute lymphoblastic leukaemia (ALL) by network pharmacology and experimental verification in vitro. METHODS: First, the biological activity of PG against B-ALL was determined by CCK-8 and flow cytometry. Then, the potential targets of PG were obtaine...

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Detalles Bibliográficos
Autores principales: Liu, Jing, Yang, Yan, Zeng, Yan, Qin, Xiang, Guo, Ling, Liu, Wenjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008983/
https://www.ncbi.nlm.nih.gov/pubmed/36923879
http://dx.doi.org/10.1016/j.heliyon.2023.e14009