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The Combination of JAK2V617F Allele Burden and WT1 Expression can Be Helpful in Distinguishing the Subtype of MPN Patients

INTRODUCTION: Classical Philadelphia-negative myeloproliferative neoplasm (MPN) includes Essential Thrombocythemia (ET), Polycythemia Vera (PV) and Primary Myelofibrosis (PMF). The JAK2V617F mutation is part of the major criteria for diagnosis of MPN. WT1 is reported to be highly overexpressed in mo...

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Detalles Bibliográficos
Autores principales: Wu, Sanyun, Luo, Ping, Rouzi, Tuerxunayi, Yu, Yalan, Xiong, Bei, Wang, Yingying, Zuo, Xuelan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009047/
https://www.ncbi.nlm.nih.gov/pubmed/36895113
http://dx.doi.org/10.1177/10732748231163648