B cell-activating factor (BAFF) from dendritic cells, monocytes and neutrophils is required for B cell maturation and autoantibody production in SLE-like autoimmune disease

PURPOSE AND METHODS: B cell-activating factor (BAFF) contributes to the pathogenesis of autoimmune diseases including systemic lupus erythematosus (SLE). Although several anti-BAFF Abs and derivatives have been developed for the treatment of SLE, the specific sources of BAFF that sustain autoantibod...

Descripción completa

Detalles Bibliográficos
Autores principales: Giordano, Daniela, Kuley, Runa, Draves, Kevin E., Elkon, Keith B., Giltiay, Natalia V., Clark, Edward A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009188/
https://www.ncbi.nlm.nih.gov/pubmed/36923413
http://dx.doi.org/10.3389/fimmu.2023.1050528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009188/
https://www.ncbi.nlm.nih.gov/pubmed/36923413
http://dx.doi.org/10.3389/fimmu.2023.1050528

Ejemplares similares