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B cell-activating factor (BAFF) from dendritic cells, monocytes and neutrophils is required for B cell maturation and autoantibody production in SLE-like autoimmune disease

PURPOSE AND METHODS: B cell-activating factor (BAFF) contributes to the pathogenesis of autoimmune diseases including systemic lupus erythematosus (SLE). Although several anti-BAFF Abs and derivatives have been developed for the treatment of SLE, the specific sources of BAFF that sustain autoantibod...

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Detalles Bibliográficos
Autores principales:	Giordano, Daniela, Kuley, Runa, Draves, Kevin E., Elkon, Keith B., Giltiay, Natalia V., Clark, Edward A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009188/ https://www.ncbi.nlm.nih.gov/pubmed/36923413 http://dx.doi.org/10.3389/fimmu.2023.1050528

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