Molecular dissection of the E6 PBM identifies essential residues regulating Chk1 phosphorylation and subsequent 14-3-3 recognition

Previous studies have shown that the high-risk HPV E6 oncoprotein PDZ binding motifs (PBMs) can interact with PDZ proteins or members of the 14-3-3 family, depending upon the E6 phosphorylation status. However, different HPV E6 oncoproteins are subjected to phosphorylation by different cellular kina...

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Detalles Bibliográficos
Autores principales: Vats, Arushi, Thatte, Jayashree V., Banks, Lawrence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009279/
https://www.ncbi.nlm.nih.gov/pubmed/36775199
http://dx.doi.org/10.1016/j.tvr.2023.200257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009279/
https://www.ncbi.nlm.nih.gov/pubmed/36775199
http://dx.doi.org/10.1016/j.tvr.2023.200257

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