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Antifungal activity of 6-substituted amiloride and hexamethylene amiloride (HMA) analogs

Fungal infections have become an increasing threat as a result of growing numbers of susceptible hosts and diminishing effectiveness of antifungal drugs due to multi-drug resistance. This reality underscores the need to develop novel drugs with unique mechanisms of action. We recently identified 5-(...

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Detalles Bibliográficos
Autores principales: Vu, Kiem, Buckley, Benjamin J., Bujaroski, Richard S., Blumwald, Eduardo, Kelso, Michael J., Gelli, Angie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009331/
https://www.ncbi.nlm.nih.gov/pubmed/36923593
http://dx.doi.org/10.3389/fcimb.2023.1101568