Asperolide A induces apoptosis and cell cycle arrest of human hepatoma cells with p53-Y220C mutant through p38 mediating phosphorylation of p53 (S33)

Asperolides A (AA), one of the new tetranorlabdane diterpenoids, is proved to inhibit the proliferation of lung cancer cells and bone metastasis of breast cancer cells. Herein, we report that AA induces apoptosis and cell cycle arrest of hepatoma cells. It intensely inhibits proliferation of Huh-7 c...

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Detalles Bibliográficos
Autores principales: Lv, Cuiting, Lan, Aihua, Fan, Xiao, Huang, Caiguo, Yang, Gong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009462/
https://www.ncbi.nlm.nih.gov/pubmed/36923828
http://dx.doi.org/10.1016/j.heliyon.2023.e13843

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009462/
https://www.ncbi.nlm.nih.gov/pubmed/36923828
http://dx.doi.org/10.1016/j.heliyon.2023.e13843

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