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Expression of the NUP153 and YWHAB genes from their canonical promoters and alternative promoters of the LINE-1 retrotransposon in the placenta of the first trimester of pregnancy

The placenta has a unique hypomethylated genome. Due to this feature of the placenta, there is a potential possibility of using regulatory elements derived from retroviruses and retrotransposons, which are suppressed by DNA methylation in the adult body. In addition, there is an abnormal increase in...

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Detalles Bibliográficos
Autores principales: Demeneva, V.V., Tolmacheva, E.N., Nikitina, T.V., Sazhenova, E.A., Yuriev, S.Yu., Makhmutkhodzhaev, A.Sh., Zuev, A.S., Filatova, S.A., Dmitriev, A.E., Darkova, Ya.A., Nazarenko, L.P., Lebedev, I.N., Vasilyev, S.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Federal Research Center Institute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009475/
https://www.ncbi.nlm.nih.gov/pubmed/36923475
http://dx.doi.org/10.18699/VJGB-23-09