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Changes in DNA methylation profile in liver tissue during progression of HCV-induced fibrosis to hepatocellular carcinoma

In this study we compared methylation levels of 27,578 CpG sites between paired samples of the tumor and surrounding liver tissues with various degrees of damage (fibrosis, cirrhosis) in HCV-induced hepatocellular carcinoma (HCC) patients, as well as between tumor and normal tissue in non-viral HCC...

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Detalles Bibliográficos
Autores principales: Goncharova, I.A., Zarubin, A.A., Babushkina, N.P., Koroleva, I.A., Nazarenko, M.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Federal Research Center Institute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009477/
https://www.ncbi.nlm.nih.gov/pubmed/36923478
http://dx.doi.org/10.18699/VJGB-23-10