SCD1 deficiency exacerbates osteoarthritis by inducing ferroptosis in chondrocytes

BACKGROUND: Osteoarthritis (OA) is a severe joint disease that causes cartilage destruction and mobility loss. Abnormal fatty acid metabolism of chondrocytes plays a role in OA development. Stearoyl-CoA desaturase (SCD1) is a rate-limiting enzyme in the anabolism of unsaturated fatty acids. This stu...

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Detalles Bibliográficos
Autores principales: Yu, Chao, Yang, Xian, Jiang, Qingsong, Liu, Zhibo, Chen, Yan, Zang, Guangchao, Huang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009576/
https://www.ncbi.nlm.nih.gov/pubmed/36923091
http://dx.doi.org/10.21037/atm-22-6630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009576/
https://www.ncbi.nlm.nih.gov/pubmed/36923091
http://dx.doi.org/10.21037/atm-22-6630

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