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A novel gene therapy for methamphetamine- induced cognitive disorder with a hyper-acidified fusion variant of DnaJB1

Methamphetamine (MA) is spread worldwide and is a highly addictive psychostimulant that can induce neurodegeneration and cognitive disorder, which lacks effective treatments. We and other researchers have found that the crucial member of Hsp70 chaperone machinery, DnaJ, is liable to be co-aggregated...

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Detalles Bibliográficos
Autores principales: Zhang, Mengru, Chen, Cheng, Peng, Qingyan, Wu, Xiaocong, Zhou, Ruiyi, Ma, Yuru, Zou, Zhurong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009643/
https://www.ncbi.nlm.nih.gov/pubmed/36923951
http://dx.doi.org/10.1016/j.omtn.2023.02.017