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Roles of STAT3 in the pathogenesis and treatment of glioblastoma

Glioblastoma (GBM) is the most malignant of astrocytomas mainly involving the cerebral hemispheres and the cerebral cortex. It is one of the fatal and refractory solid tumors, with a 5-year survival rate of merely 5% among the adults. IL6/JAK/STAT3 is an important signaling pathway involved in the p...

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Detalles Bibliográficos
Autores principales: Fu, Weijia, Hou, Xue, Dong, Lihua, Hou, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009693/
https://www.ncbi.nlm.nih.gov/pubmed/36923251
http://dx.doi.org/10.3389/fcell.2023.1098482