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Roles of STAT3 in the pathogenesis and treatment of glioblastoma

Glioblastoma (GBM) is the most malignant of astrocytomas mainly involving the cerebral hemispheres and the cerebral cortex. It is one of the fatal and refractory solid tumors, with a 5-year survival rate of merely 5% among the adults. IL6/JAK/STAT3 is an important signaling pathway involved in the p...

Fuld beskrivelse

Bibliografiske detaljer
Autores principales: Fu, Weijia, Hou, Xue, Dong, Lihua, Hou, Wei
Format: Online Artículo Texto
Sprog:English
Udgivet: Frontiers Media S.A. 2023
Fag:
Online adgang:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009693/
https://www.ncbi.nlm.nih.gov/pubmed/36923251
http://dx.doi.org/10.3389/fcell.2023.1098482