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Physiological levels of poly(ADP-ribose) during the cell cycle regulate HeLa cell proliferation
Protein targets of polyADP-ribosylation undergo covalent modification with high-molecular-weight, branched poly(ADP-ribose) (PAR) of lengths up to 200 or more ADP-ribose residues derived from NAD(+). PAR polymerase 1 (PARP1) is the most abundant and well-characterized enzyme involved in PAR biosynth...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009817/ https://www.ncbi.nlm.nih.gov/pubmed/35447104 http://dx.doi.org/10.1016/j.yexcr.2022.113163 |