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Narsoplimab for severe transplant-associated thrombotic microangiopathy

BACKGROUND: Transplantation-associated thrombotic microangiopathy (TA-TMA) is an endothelial injury syndrome linked to the overactivation of complement pathways. It manifests with microangiopathic hemolytic anemia, consumptive thrombocytopenia, and microvascular thrombosis leading to ischemic tissue...

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Detalles Bibliográficos
Autores principales: Pandrowala, Ambreen, Ganatra, Parth, Krishnan, V. P., Sharma, Ajay Narayan, Chavan, Saroj, Bodhanwala, Minnie, Agarwal, Bharat, Hiwarkar, Prashant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009829/
https://www.ncbi.nlm.nih.gov/pubmed/36915123
http://dx.doi.org/10.1186/s12959-023-00464-9