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A live dengue virus vaccine carrying a chimeric envelope glycoprotein elicits dual DENV2-DENV4 serotype-specific immunity

The four dengue virus serotypes co-circulate globally and cause significant human disease. Dengue vaccine development is challenging because some virus-specific antibodies are protective, while others are implicated in enhanced viral replication and more severe disease. Current dengue tetravalent va...

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Detalles Bibliográficos
Autores principales: Young, Ellen, Yount, Boyd, Pantoja, Petraleigh, Henein, Sandra, Meganck, Rita M., McBride, Jennifer, Munt, Jennifer E., Baric, Thomas J., Zhu, Deanna, Scobey, Trevor, Dong, Stephanie, Tse, Longping V., Martinez, Melween I., Burgos, Armando G., Graham, Rachel L., White, Laura, DeSilva, Aravinda, Sariol, Carlos A., Baric, Ralph S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009830/
https://www.ncbi.nlm.nih.gov/pubmed/36914616
http://dx.doi.org/10.1038/s41467-023-36702-x