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A live dengue virus vaccine carrying a chimeric envelope glycoprotein elicits dual DENV2-DENV4 serotype-specific immunity
The four dengue virus serotypes co-circulate globally and cause significant human disease. Dengue vaccine development is challenging because some virus-specific antibodies are protective, while others are implicated in enhanced viral replication and more severe disease. Current dengue tetravalent va...
Autores principales: | Young, Ellen, Yount, Boyd, Pantoja, Petraleigh, Henein, Sandra, Meganck, Rita M., McBride, Jennifer, Munt, Jennifer E., Baric, Thomas J., Zhu, Deanna, Scobey, Trevor, Dong, Stephanie, Tse, Longping V., Martinez, Melween I., Burgos, Armando G., Graham, Rachel L., White, Laura, DeSilva, Aravinda, Sariol, Carlos A., Baric, Ralph S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009830/ https://www.ncbi.nlm.nih.gov/pubmed/36914616 http://dx.doi.org/10.1038/s41467-023-36702-x |
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