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Paracrine secretion of IL8 by breast cancer stem cells promotes therapeutic resistance and metastasis of the bulk tumor cells

BACKGROUND: Breast tumors consist of heterogeneous cellular subpopulations that differ in molecular properties and functional attributes. Cancer stem cells (CSCs) play pivotal roles in cancer therapeutic failure and metastasis. However, it remains indeterminate how CSCs determine the progression of...

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Detalles Bibliográficos
Autores principales: Wu, Mingming, Zhang, Xiao, Zhang, Weijie, Yan, Linlin, Liu, Xiangtian, Zhang, Min, Pan, Yueyin, Lobie, Peter E., Han, Xinghua, Zhu, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009947/
https://www.ncbi.nlm.nih.gov/pubmed/36915147
http://dx.doi.org/10.1186/s12964-023-01068-6