Endothelial cell-derived MMP19 promotes pulmonary fibrosis by inducing E(nd)MT and monocyte infiltration

BACKGROUND: Matrix metalloproteinases (MMPs) play important roles in remodeling the extracellular matrix and in the pathogenesis of idiopathic pulmonary fibrosis (IPF). MMP19, which is an MMP, was significantly upregulated in hyperplastic alveolar epithelial cells in IPF lung tissues and promoted ep...

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Detalles Bibliográficos
Autores principales: Zhao, Weiming, Wang, Lan, Yang, Juntang, Chen, Xinyu, Guo, Xiaoshu, Xu, Kai, Wang, Ningdan, Zhao, Wenyu, Xia, Cong, Lian, Hui, Rosas, Ivan, Yu, Guoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009991/
https://www.ncbi.nlm.nih.gov/pubmed/36915092
http://dx.doi.org/10.1186/s12964-023-01040-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10009991/
https://www.ncbi.nlm.nih.gov/pubmed/36915092
http://dx.doi.org/10.1186/s12964-023-01040-4

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