Hypoxia and HIFs in Ewing sarcoma: new perspectives on a multi-facetted relationship

Hypoxia develops during the growth of solid tumors and influences tumoral activity in multiple ways. Low oxygen tension is also present in the bone microenvironment where Ewing sarcoma (EwS) – a highly aggressive pediatric cancer – mainly arises. Hypoxia inducible factor 1 subunit alpha (HIF-1-a) is...

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Detalles Bibliográficos
Autores principales: Ceranski, A. Katharina, Carreño-Gonzalez, Martha J., Ehlers, Anna C., Colombo, Maria Vittoria, Cidre-Aranaz, Florencia, Grünewald, Thomas G. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010019/
https://www.ncbi.nlm.nih.gov/pubmed/36915100
http://dx.doi.org/10.1186/s12943-023-01750-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010019/
https://www.ncbi.nlm.nih.gov/pubmed/36915100
http://dx.doi.org/10.1186/s12943-023-01750-w

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