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Demonstration of doxorubicin's cardiotoxicity and screening using a 3D bioprinted spheroidal droplet-based system

Doxorubicin (DOX) is a highly effective anthracycline chemotherapy agent effective in treating a broad range of life-threatening malignancies but it causes cardiotoxicity in many subjects. While the mechanism of its cardiotoxic effects remains elusive, DOX-related cardiotoxicity can lead to heart fa...

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Detalles Bibliográficos
Autores principales: El Khoury, Raven, Ramirez, Salma P., Loyola, Carla D., Joddar, Binata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010162/
https://www.ncbi.nlm.nih.gov/pubmed/36922946
http://dx.doi.org/10.1039/d3ra00421j