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A Spatially Resolved Mechanistic Growth Law for Cancer Drug Development Predicting Tumor Growing Fractions

Mathematical models used in preclinical drug discovery tend to be empirical growth laws. Such models are well suited to fitting the data available, mostly longitudinal studies of tumor volume; however, they typically have little connection with the underlying physiologic processes. This lack of a me...

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Detalles Bibliográficos
Autores principales: Nasim, Adam, Yates, James, Derks, Gianne, Dunlop, Carina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010375/
https://www.ncbi.nlm.nih.gov/pubmed/36923310
http://dx.doi.org/10.1158/2767-9764.CRC-22-0032