Ribonuclease H2 Subunit A Preserves Genomic Integrity and Promotes Prostate Cancer Progression

Homeostasis of genomic integrity should be regulated to promote proliferation and inhibit DNA damage–induced cell death in cancer. Ribonuclease H2 (RNase H2) maintains genome stability by controlling DNA:RNA hybrid and R-loop levels. Here, we identified that RNase H2 subunit A (RNASEH2A), a componen...

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Detalles Bibliográficos
Autores principales: Kimura, Naoki, Takayama, Ken-ichi, Yamada, Yuta, Kume, Haruki, Fujimura, Tetsuya, Inoue, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010380/
https://www.ncbi.nlm.nih.gov/pubmed/36923313
http://dx.doi.org/10.1158/2767-9764.CRC-22-0126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010380/
https://www.ncbi.nlm.nih.gov/pubmed/36923313
http://dx.doi.org/10.1158/2767-9764.CRC-22-0126

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