Chimeric antigen receptor-T cells are effective against CEACAM5 expressing non-small cell lung cancer cells resistant to antibody-drug conjugates

Chimeric antigen receptor-T (CAR-T) cells and antibody-drug conjugates (ADCs) are promising therapeutic strategies in oncology. The carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) is overexpressed in tumors including non-small cell lung cancer (NSCLC) and pancreatic ductal adenoc...

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Detalles Bibliográficos
Autores principales: Kim, Ye-Jin, Li, Wei, Zhelev, Doncho V., Mellors, John W., Dimitrov, Dimiter S., Baek, Du-San
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010383/
https://www.ncbi.nlm.nih.gov/pubmed/36923424
http://dx.doi.org/10.3389/fonc.2023.1124039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010383/
https://www.ncbi.nlm.nih.gov/pubmed/36923424
http://dx.doi.org/10.3389/fonc.2023.1124039

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