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β-arrestin1-E2F1-ac axis regulates physiological apoptosis and cell cycle exit in cellular models of early postnatal cerebellum

Development of the cerebellum is characterized by rapid proliferation of cerebellar granule cell precursors (GCPs) induced by paracrine stimulation of Sonic hedgehog (Shh) signaling from Purkinje cells, in the external granular layer (EGL). Then, granule cell precursors differentiate and migrate int...

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Detalles Bibliográficos
Autores principales: Abballe, Luana, Alfano, Vincenzo, Antonacci, Celeste, Cefalo, Maria Giuseppina, Cacchione, Antonella, Del Baldo, Giada, Pezzullo, Marco, Po, Agnese, Moretti, Marta, Mastronuzzi, Angela, De Smaele, Enrico, Ferretti, Elisabetta, Locatelli, Franco, Miele, Evelina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010392/
https://www.ncbi.nlm.nih.gov/pubmed/36923256
http://dx.doi.org/10.3389/fcell.2023.990711