Impaired Antitumor Immune Response in MYCN-amplified Neuroblastoma Is Associated with Lack of CCL2 Secretion and Poor Dendritic Cell Recruitment

In neuroblastoma, MYCN amplification is associated with sparse immune infiltrate and poor prognosis. Dendritic cells (DC) are crucial immune sentinels but their involvement in neuroblastoma pathogenesis is poorly understood. We observed that the migration of monocytes, myeloid and plasmacytoid DC in...

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Detalles Bibliográficos
Autores principales: Kacher, Jamila, Manches, Olivier, Aspord, Caroline, Sartelet, Hervé, Chaperot, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010397/
https://www.ncbi.nlm.nih.gov/pubmed/36923280
http://dx.doi.org/10.1158/2767-9764.CRC-21-0134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010397/
https://www.ncbi.nlm.nih.gov/pubmed/36923280
http://dx.doi.org/10.1158/2767-9764.CRC-21-0134

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