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Impaired Antitumor Immune Response in MYCN-amplified Neuroblastoma Is Associated with Lack of CCL2 Secretion and Poor Dendritic Cell Recruitment
In neuroblastoma, MYCN amplification is associated with sparse immune infiltrate and poor prognosis. Dendritic cells (DC) are crucial immune sentinels but their involvement in neuroblastoma pathogenesis is poorly understood. We observed that the migration of monocytes, myeloid and plasmacytoid DC in...
Autores principales: | Kacher, Jamila, Manches, Olivier, Aspord, Caroline, Sartelet, Hervé, Chaperot, Laurence |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010397/ https://www.ncbi.nlm.nih.gov/pubmed/36923280 http://dx.doi.org/10.1158/2767-9764.CRC-21-0134 |
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